Brain Training in Children at Risk for Inattention, Hyperactivity, and Executive Function Impairment

Who is Eligible: Children ages 4 and 5. We are looking for children born prematurely (< 33 weeks gestational age) and/or those who have been diagnosed or are at risk (have symptoms or positive family history) for Attention Deficit Hyperactivity Disorder (ADHD).  

Principal Investigator: Irene Loe, MD

Research Coordinator: Cory Dodson / Email: / Phone: (650) 498-7690


We are conducting a research study to determine if kid-friendly computer based games (“Brain Training”) can improve children’s thinking and problem solving abilities. Our study involves children ages 4 and 5 who were either born prematurely, or have/are at risk for ADHD.


  1. Children will complete two testing sessions based at Stanford, each lasting about 1.5 hours.

Computer and play-based games will be used to see how your child controls his/her behavior, attention, and problem solving skills.

We will give you a packet of information to complete, including questionnaires about your child’s behavior and functional skills.

     2.   After completion of the testing visits, we will inform you of eligibility for the Brain Training phase.

In this phase, children will play an online computer game for about 25-30 minutes/day (can range from 15-45 minutes/day depending on your child’s performance, attention, training version received, number and length of breaks needed). They will engage in play 5 days a week, for 5-7 weeks. They should complete a total of 25 sessions.

Children will then return to Stanford for three more testing sessions, one immediately after completion of Brain Training, and also at 3 and 6 months after Brain Training.


Who is running the studies?  More 

Developmental-behavioral pediatrician Dr. Irene Loe is the principal investigator. Trained research assistants are also involved in conducting the study.


What are the costs or possible risks involved in participation?  More 

There are no costs to your child. Our methods are completely safe for your child, and you and your child’s information is kept confidential.


What are the benefits of participating?  More 

  1. We will compensate you and your child with $60 following your child's completion of the 25 sessions.
  2. You will receive free computer-based treatment designed to help us see if it will improve your child’s thinking and problem solving abilities.
  3. We may identify behavior or learning problems that you and your child are unaware of. If we do, we will recommend services or approaches to help your child.


How does the Brain Training work?  More 

The games are accessed online and designed to be fun for preschool-aged children. A parent or other guardian may help supervise and encourage the children while they play the games.


I have friends who also have children who may be eligible. Could they also be participants in this study?  More 

Yes! Please feel free to share this brochure and our contact information with anyone who may also be interested in participating.